Directions from Las Vegas, NV to Grand Canyon South Rim
Take Highway 93 south to I-40. Take I-40 east to Highway 64. Take Highway 64 north directly to the South Rim.
242 miles (406 km) - 3 hours, 53 minutes
Directions from Grand Canyon South Rim to Flagstaff (there are three ways you can get to Flagstaff from the South Rim)
Take Highway 64 south out of the south entrance to the South Rim. Take I-40 east to Flagstaff
79 miles (96 km) - 1 hour 32 minutes. Or...
Take Highway 64 south out of the south entrance to the South Rim. Take Highway 180 east to Flagstaff.
49.6 miles (79.8 km) - 55 minutes. Or...
Take Highway 64 east out of the east entrance of the South Rim - known as Desert View. Take Highway 89 south to Flagstaff.
50 miles (80 km) - 55 minutes.
Directions from Grand Canyon West Rim to Flagstaff
Take Diamond Bar Rd to Pierce Ferry Rd. Take Pierce Ferry Rd to Stockton Hill Rd. Take Stockton Hill Rd to I-40 East. Take I-40 east to Flagstaff.
216 miles (347 km) - 3 hours, 50 minutes
Directions from Williams to Flagstaff
Take I-40 east to Flagstaff.
35 miles (56 km) - 36 minutes
Directions from Los Angeles, CA to Flagstaff
Take I-15 east to I-40. Take I-40 east to Flagstaff.
455 miles (750 km) - 6 hours, 43 minutes
Directions from San Diego, CA to Grand Canyon South Rim
Take I-215 north to I-15. Take I-15 east to I-40. Take I-40 east to Flagstaff.
491 miles (790 km) - 7 hours, 15 minutes